When this fine layer is somehow damaged there is a dissociation of the dermal and epidermal lamellae resulting in. Dermal papilla epidermal ridge epidermis dermis basement membrane. Drag the labels onto the diagram to identify the basic structures of the epidermis dermis junction.
epidermal basement membrane diagram
Drag the labels onto the epidermal layers.
Epidermal basement membrane diagram. The basement membrane is a dense highly cross linked sheet like extracellular matrix that underlies all epithelia and endothelia in multicellular animals. Based largely on in vitro studies cells have been thought to use proteases to dissolve and traverse. The basement membrane is a thin fibrous extracellular matrix that separates the lining of an internal or external body surface from underlying connective tissue in metazoans animals. The epidermis has a complex structure designed to protect from the environment.
Each of the following is a. Differentiating cells delaminate from the basement membrane and are displaced outward through the epidermal layers undergoing multiple stages of differentiation until in the stratum corneum losing their nucleus and fusing to squamous sheets which are eventually shed from the surface desquamation. The basement membrane zone is the communication channel between epidermis and dermis. They are typically synthesized by epithelial and endothelial cells but production of basement membrane components has been also reported for a large variety of other cells kefalides et al.
Basement membranes are ubiquitous extracellular matrix structures which separate different compartments in tissues. During development leukocyte trafficking and metastatic disease cells cross the basement membrane to disperse and enter new tissues. Assess and monitor disease in patient with pemphigoid or epidermolysis bullosa acquisita who has positive igg basement membrane zone bmz antibodies by indirect immunofluorescence either. Stratum spinosum stratum lucidum epidermal ridge stratum basale basement membrane dermis dermal papilla stratum granulosum stratum corneum.
It has an undulating surface with cross crossing ridges and valleys with invaginations due to follicles and sweat duct ostia. The basement membrane found in the hooves of horses is essentially the same as in other animals however with an important specialization. These cells serve a sensory function as mechanoreceptors for light touch and are most populous in fingertips though also found in the palms soles oral and genital mucosa. It is responsible for the union of the secondary dermal and epidermal lamellae and consequently for the support of the whole axial skeleton.
Differentiated keratinocytes secrete keratin proteins which contribute to the formation of. They are bound to adjoining keratinocytes by desmosomes and contain intermediate keratin. This surface may be epithelium skin respiratory tract gastrointestinal tract etc mesothelium pleural cavity peritoneal cavity pericardial cavity etc and endothelium blood vessels lymph vessels. Merkel cells merkel cells are oval shaped modified epidermal cells found in stratum basale directly above the basement membrane.
May include related or preferred tests. Immunodermatology required clinical information form serum ordering recommendation recommendations when to order or not order the test.
